Kell Brook will make his debut at super-welterweight against Sergey Rabchenko at the FlyDSA Arena in Sheffield on March 3.
Brook (36-2. 25KOs) is looking to become a two-weight world champion after losing his IBF welterweight title to Errol Spence at Bramall Lane earlier this year and has now decided to move up a weight class.
"I can't wait to get back in there and it's going to be special returning to the arena," said Brook. "The Spence defeat cut deep and it took me some time to come to terms with it but now I'm back with a new challenge at 154lbs.
"I believe I will be stronger and better than ever in the division and my focus now is on becoming a two-weight two-time world champion.
"Rabchenko is a dangerous fight for the return but I want to jump straight back in at world level and I think out styles will gel for an electric fight. I'm already deep in camp and I can't wait to feel the atmosphere again in my home town on March 3."
Belarus fighter Rabchenko (29-2, 21KOs) is the former European title holder at super-welterweight and is No. 7 in the WBC's rankings. He is aiming to boost his own chances of a world title shot by defeating Brook.
Brook's promoter, Eddie Hearn, expressed his concern about the test that awaits Brook in his hometown. He said: "I'm so pleased to see Kell back in camp and moving up for a fresh start at 154lbs.
"He refused to vacate the title for Spence but was could never fight at his full potential making 147lbs anymore.
"This is a tough, tough test, probably tougher than I would have liked, but Kell wanted to be straight back in at top level."
