Jacobs has signed for promoter Eddie Hearn, who is eager to deliver a fight against the winner of Golovkin's expected rematch with Alvarez, and the New Yorker believes he would be too strong in a potential fight with the Mexican star.
"I say stoppage," Jacobs told Boxingscene.com. "I really feel that coming into who I've become as a man, as an athlete, as a professional, I really feel that I can go in there and get the job done.
"What he brings to the table, and I'm not knocking anything, but size matters in boxing, physiques matter, it's different. I'm telling you it's different and I do see myself stopping Canelo."
Jacobs, who is due to return in November, did not think Alvarez deserved a draw and insists he lay the blueprint for a fight against Golovkin.
"Canelo didn't really show me anything that I didn't do first," said the former WBA 'regular' middleweight champion.