The 34-year-old Cuban has been the world World Boxing Association champion since Friday after Manny Pacquiao was stripped of this title. The last time Ugas fought was in September, defeating Abel Ramos on points.
Spence returned to the ring in December after more than a year hiatus due to health problems following a car accident. In his last fight, the American defeated Danny Garcia.
Watch this story:
Oscar De La Hoya Cautions Manny Pacquiao's Return: "Age Is Undefeated"